Why Spore-Based Probiotics Are THE Gold Standard:

Spore-Based Probiotics vs. Regular Probiotics

  • Spore-based probiotics, like regular probiotics, contain live microorganisms, but in spore form.

  • Unlike regular probiotics, spore-based probiotics have a rugged and durable “endospore” coating. Think of this as a coat of armor that gives an extra layer of protection against the harsh climate inside the human body. 

  • This coating also helps the bacteria sense shifts in their terrain that might make conditions sketchy; spore-based probiotics can then go dormant until the environment is safe again.

  • The endospore is what sets spore-based probiotics apart because it helps them survive the harsh environment of the digestive process. This means, when they reach your gut, they are still alive and can do the work they are supposed to do. Most regular probiotics die before they even reach their destination. 

Top 4 Benefits of Using Spore-Based Probiotics

  • Survival: Thanks to their protective outer coating, spore-based probiotics are designed to maintain efficacy and survivability throughout the digestive process so they can do the work they are supposed to once they arrive in your gut! 

  • Durability: These spore-based probiotics are so durable, they can withstand extreme heat, cold, pressure,1 and even radiation,2-7 so you know you’re getting your money’s worth! 

  • Microbiome Diversity: Spores also indirectly increase the richness and diversity of your gut microbiome. Diversity is better for overall health! 

  • Overcrowding: Spores push out the "bad guys" (the unwanted bacteria) to leave more room for the good bacteria that keep your gut, brain, and body systems happy! 

MegaSporeBiotic™ 

Microbiome Labs’ flagship probiotic is one of THE MOST recognized names in the probiotic industry and was the FIRST 100% multi-spore-based probiotic on the market.   

Supported by extensive clinical validation and backed by over 9 published studies, with multiple, ongoing studies. The FIRST 100% spore-based, broad-spectrum probiotic clinically shown to RECONDITION the gut. 

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  • Disruptor

    Microbiome Labs completely disrupted the probiotic industry, shifting the focus from reseeding to reconditioning the gut microbiome.

  • Trendsetting

    MegaSporeBiotic™was the FIRST 100% multi-spore-based probiotic on the market.

  • Pioneering

    Using a blend of 5 Bacillus spores, it paved the way for spore-based probiotics in the industry.

  • Innovative

    The unique blend of 5 Bacillus spore-forming bacterial strains that recondition the gut vs. just reseeding it, is truly innovative! 

The Journey from Bottle to Microbiome

Let’s take a deeper look at each of the 5 different probiotic players:  

Bacterial spores are dormant life forms which can exist in a desiccated and dehydrated state indefinitely.

Each spore-forming strain has its own unique set of benefits: 

  • BACILLUS SUBTILIS HU58

    Produces over 12 effective, naturalantibioticsubstances. HU58 is highlyimportant for immune development, as the gut contains 70% of your immune system!

  • BACILLUS INDICUS HU36

    Is a potent immune support, producing carotenoids, astaxanthin, beta carotene, lycopene, lutein, quinols and various vitamins, all of which can help maintain healthy antioxidant levels.

  • BACILLUS CLAUSII SC109

    Is a widely used probiotic and a potent immune support. The strain is safe for use during antibiotic treatment.

  • BACILLUS COAGULANS SC208

    Has been extensively studied with a long history of safe and effective use. Many studies have tested its efficacy on supporting the gut microbiome, showing it can produce lactic acid and support immune function.

  • BACILLUS LICHENIFORMIS SL307

    Can produce natural antibiotic substances and improve protein digestion via production of protease enzymes. These spores can produce a broad spectrum of highly bioavailable B-vitamins including folic acid (B9)!

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Spores: Good for More Than You Thought Possible!  

Spore-forming probiotics are super-charged with key ingredients for multiple health benefits—NOT JUST FOR YOUR GUT!    

Due to strain specificity, spores can be uniquely positioned in formulation for SPECIFIC health support, including:

  • Brain Health  
  • Oral & Skin Health  
  • Metabolic Health  
  • Protective Immune Health  
  • Gastrointestinal Health  
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Why Trust Us?

Clean Products

It is important to avoid genetically modified or lab-created spores, as well as unnecessary fillers like flour and magnesium silicate. You will not find these in Microbiome Labs products.

Clinical Trials

All Microbiome Labs products are created with ingredients that have been run through clinical trials, and nearly all of our final formulations have clinical studies proving their efficacy.

All Spores

MegaSporeBiotic™ is the first ALL-SPORE probiotic formulation containing 5 unique species of spore-formingBacillus. Some ompanies will only have one or two spore-forming strains but pad the rest with non-spore-forming probiotics.

Third-Party Testing

Our products are third-party tested by ISO 17025 accredited labs. Third party testing is the gold standard for ensuring that the product’s contents match its label.

Human Digestion Models

In vitro human digestion models have shown our spore-based probiotics can survive the harsh environment of the stomach.

Survivability

Survivability is what sets “spore-based” probioticsapart from regularprobiotics. MegaSporeBiotic™ wasdesigned to maintainefficacy, and survivabilitythroughout the digestive process.8

Human Gut Origins

Our Bacillus spores are uniquely derived directly from a healthy human gut and cultured, rather than isolated from the soil or yogurt, which means they’re designed specifically to support human health

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Spore Origin Story:

FROM DISCOVERY TO DIGESTION

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